ForecastedOpportunity CDC-RFA-PS-27-0239

Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use

Centers for Disease Control - NCHHSTP · Department of Health and Human Services

At a glance

Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use is a forecasted federal cooperative agreement opportunity from the Centers for Disease Control - NCHHSTP (Department of Health and Human Services). The agency's forecast estimates an application due date of May 24, 2027; forecast dates can change. Total estimated funding is $82.5M across about 2 awards. The notice is unrestricted by applicant type, subject to any clarifications in the notice. Cost sharing is not required. It is funded under Assistance Listing 93.488 (National Harm Reduction Technical Assistance and Syringe Services Program (SSP) Monitoring and Evaluation Funding Opportunity).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Jul 24, 2026Forecast posted
Mar 24, 2027 (est.)Full notice expectednext date
May 24, 2027 (est.)Application deadline
Aug 30, 2027 (est.)Est. award date

Posted: Jul 24, 2026
Est. close date: May 24, 2027
Est. award date: Aug 30, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $82,500,000
Implied average award: $41,250,000 calculated
Expected awards: 2
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2027

Typical awards for this program (SAM.gov listing for ALN 93.488, not this notice): This assistance listing only applies to 1 Cooperative Agreement; obligation amounts are outlined above.

Implied average = estimated total funding ÷ expected number of awards, calculated by GrantsJunction. Actual awards vary.

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Unrestricted (any entity type)

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This NOFO aims to strengthen services to prevent the infectious disease consequences of drug use in high impact settings serving people who use drugs (PWUD) through two components. Component 1 will improve service data by conducting a biennial survey of high-impact settings that serve PWUD to document capacity, needs, access, and service gaps. It will also improve timely local data on infectious disease consequences of drug use and the use of infectious disease testing, treatment, and prevention services at high-impact settings through a biennial biobehavioral survey of PWUD. Component 2 will increase support the availability and use of infectious disease testing, treatment and prevention services in high-impact settings serving PWUD. Applicants may apply for Component 1, Component 2, or both. Expected outcomes include enhanced capacity nationally and locally to use data to improve infectious disease testing, treatment and prevention services among PWUD, increased PWUD testing for HBV, HCV, and HIV, increased PWUD with hepatitis C who initiated treatment, and increased PWUD with HIV who engaged in care and treatment. This NOFO is in alignment with CDC priorities.

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Watch for the full noticeThe agency estimates posting it around March 24, 2027. Save this grant to track changes.
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyMonica Adams · ydy7@cdc.gov Open ↗
Submit before May 24, 2027Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date. Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.488National Harm Reduction Technical Assistance and Syringe Services Program (SSP) Monitoring and Evaluation Funding OpportunityProgram →

Reported obligations under ALN 93.488

Historical data · not a prediction

FY24

$12.4M

FY25

$12.5M

FY26

$12.5M est.

Source: SAM.gov Assistance Listing 93.488. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.488

Historical data · not a prediction

Since October 1, 2023, 3 grant awards had funding actions under National Harm Reduction Technical Assistance and Syringe Services Program (SSP) Monitoring and Evaluation Funding Opportunity. These are program-wide awards, not awards from this specific notice.

NATIONAL ALLIANCE OF STATE & TERRITORIAL AIDS DIRECTORS$9.15M
RESEARCH TRIANGLE INSTITUTE$1.21M
HEALTH, WASHINGTON STATE DEPARTMENT OF$150K
PUERTO RICO DEPARTMENT OF HEALTH$150K
CITY & COUNTY OF SAN FRANCISCO$150K

Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

Monica Adams
ydy7@cdc.gov
404-718-5092

Quick answers

Is “Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around March 24, 2027. Forecast details and dates can change.

Who is eligible to apply for “Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use”?

The notice lists eligibility as unrestricted — open to any type of entity — subject to clarifications in the notice's additional eligibility information.

How much funding is available through “Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use”?

Per the notice, total estimated program funding is $82,500,000 and the agency expects to make about 2 awards.

How do I apply for “Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity CDC-RFA-PS-27-0239), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedALN 93.940