ForecastedResearch announcementOpportunity FOR-MD-25-005

Forecast to Renew the Funding Opportunity Announcement for Multiple Chronic Disease Research Centers Coordinating Center (U24 Clinical Trial Not Required)

National Institutes of Health · Department of Health and Human Services

At a glance

Forecast to Renew the Funding Opportunity Announcement for Multiple Chronic Disease Research Centers Coordinating Center (U24 Clinical Trial Not Required) is a forecasted federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of November 26, 2025; forecast dates can change. Total estimated funding is $20M across about 1 awards. Applicant types listed as eligible include state governments, county governments, independent school districts, public colleges & universities, federally recognized tribal governments and 6 more. Cost sharing is not required. It is funded under Assistance Listing 93.307 (Minority Health and Health Disparities Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

May 27, 2025Forecast posted
Sep 25, 2025 (est.)Full notice expected
Nov 26, 2025 (est.)Application deadline
Dec 29, 2025 (est.)Est. award date

Posted: May 27, 2025
Est. close date: Nov 26, 2025
Est. award date: Dec 29, 2025
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $20,000,000
Implied average award: $20,000,000 calculated
Expected awards: 1
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2026

Typical awards for this program (SAM.gov listing for ALN 93.307, not this notice): (1) Centers of Excellence on Environmental Health Disparities Research (P50) 3 total awards made by the NIMHD ranged from $1,359,847 to $1,513,011; average $1,433,333; (2) Endowment grants (S21): 2 total awards made by the NIMHD for $2,000,000 each; (3) Specialized Centers of Excellence (U54): 12 total awards made by the NIMHD ranged from $970,271 to $1,929,905; average $1,455,792; (4) NIMHD Minority Health and Health Disparities Research Training (MHRT, T37) grants: 12 total awards made by the NIMHD ranged from $197,856, to $283,553; average $265,097; (5) Small Business Innovation Research (SBIR) grants: 25 total awards made by the NIMHD ranged from $228,344 to $818,132; average $459,022; (6) Small Business Technology Transfer (STTR) Grants: 4 total awards made by the NIMHD ranged from $316,117 to $502,559 average $424,999; (7) Health Disparities Research Project grants and cooperative agreements (RPG): 309 total awards made by the NIMHD ranged from $1 to $1,867,461; average $524,008; (8) Research Centers in Minority Institutions (RCMI, U54/U24): 22 total awards made ranged from $1,306,265 to $6,473,264; average $3,826,584; (9) Research Centers in Minority Institution Clinical and Translational Research (RCTR) (U24): $0; (10) Research Centers in Minority Institutions Translational Research Network (RCTN) (U24): $1,306,265; (11) Clinical Research Education and Career Development (CRECD) Awards (R25): 4 total awards ranged from $526,358 to $540,000; average $534,207; (12) Pathway to Independence and Career Development Awards (Ks): 56 total awards made by the NIMHD ranged from $97,272 to $316,822; average $147,746; (13) NIH Research Conference Grants: one award, $50,000; (14) Transdisciplinary Collaborative Centers (U54): one award, $618,864; (15) Ruth L Kirschstein NRSA Individual Fellowships; 23 total awards ranged from $31,736 to $70,890; average $41,974; (16) NRSA training grants (T32): 2 total awards ranged from $209,346 to $209,830; average $209,588; (17) RADx emergency awards: 16 total awards ranged from $708,970 to $49,397,223; average $4,335,795; (18) NIH Directors New Innovator Award Program (DP2): one award, $1,449,000; (19) Centers for Multiple Chronic Diseases associated with Health Disparities (P50/U24): 12 total awards ranged from $2,415,592 to $5,055,281; average $3,900,708; (20) Building Population Health Research Capacity in the US Affiliated Pacific Islands (U24:): one award, $246,550; (21) NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program (U24): one award, $1,229,873.

Implied average = estimated total funding ÷ expected number of awards, calculated by GrantsJunction. Actual awards vary.

Who can apply

State governments
County governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This forecast is to renew the Notice of Funding Opportunity (NOFO) for the Multiple Chronic Diseases Research Coordinating Center (MCD-RCC; RFA-MD-21-008). This research coordinating center supports regional P50 comprehensive research centers studying the timely prevention, diagnosis, treatment, and management of co-existing chronic diseases to reduce health disparities as authorized by Public Law 116-260, the Consolidated Appropriations Act of 2021. The MDC-RCC will coordinate activities, including data collection and management, promoting collaboration and communication, promoting skills development among early-stage investigators, building a community of practice, and facilitating community and healthcare setting/system engagement.

The MCD-RCC will serve as a national resource to help the centers achieve their primary goals to develop, test, and evaluate novel models or strategies, and/or implement effective interventions in various settings such as community or healthcare settings/systems. The MCD-RCC will lead a community of practice and activities to facilitate in four core domains: (1) consortium organization, management, and communication, (2) research coordination and data standardization, sharing, harmonization, analysis, (3) research skills development, and (4) community and healthcare setting/system engagement. The overarching goal is to support the objectives of the multiple chronic disease research initiative.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the P50 activity code. Investigators with expertise and insights into the proposed scientific areas are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in clinical care, health services, data science, and community engaged research, will be encouraged and such interdisciplinary research teams should also consider applying for this NOFO.

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Watch for the full noticeThe agency estimates posting it around September 25, 2025. Save this grant to track changes.
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyAnuradha Patel, MD National Institute on Minority Health and Health Disparities (NIMHD) · Anuradha.patel@nih.gov Open ↗
Submit before November 26, 2025Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.307Minority Health and Health Disparities ResearchProgram →

Reported obligations under ALN 93.307

Historical data · not a prediction

FY20

$334M

FY21

$899M

FY22

$421M

FY23

$540M

FY24

$489M est.

FY25

$489M est.

Source: SAM.gov Assistance Listing 93.307. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.307

Historical data · not a prediction

Since October 1, 2023, 1,362 grant awards had funding actions under Minority Health and Health Disparities Research, with 2,005 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.

UNIVERSITY OF HAWAII$39.6M
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK$36.6M
THE JOHNS HOPKINS UNIVERSITY$34.4M
REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE$29.8M
SAN DIEGO STATE UNIVERSITY FOUNDATION$25.4M

Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

Anuradha Patel, MD National Institute on Minority Health and Health Disparities (NIMHD)
Anuradha.patel@nih.gov
301-594-1197

Quick answers

Is this opportunity open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around September 25, 2025. Forecast details and dates can change.

Who is eligible to apply for this opportunity?

The official notice names these applicant types as eligible: State governments, County governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Private colleges & universities, For-profit organizations (not small businesses) and Small businesses. Additional restrictions may apply; review the full notice.

How much funding is available through this opportunity?

Per the notice, total estimated program funding is $20,000,000 and the agency expects to make about 1 awards.

How do I apply for this opportunity?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity FOR-MD-25-005), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedResearchALN 93.307