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ForecastedResearch announcementOpportunity PAR-28-011

Feasibility Studies to Inform the Design of Future Clinical Trials

National Institutes of Health · Department of Health and Human Services

At a glance

Feasibility Studies to Inform the Design of Future Clinical Trials is a forecasted federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of February 16, 2027; forecast dates can change. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.213 (Research and Training in Complementary and Integrative Health).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

  1. Apr 28, 2026Forecast posted
  2. Nov 24, 2026 (est.)Full notice expectednext date
  3. Feb 16, 2027 (est.)Application deadline
  4. Dec 1, 2027 (est.)Est. award date
Posted
Apr 28, 2026
Est. close date
Feb 16, 2027
Est. award date
Dec 1, 2027
Award floor
Not specified
Award ceiling
Not specified
Est. total funding
Not specified
Expected awards
Not specified
Cost sharing
Not required
Funding instrument
Grant
Opportunity category
Discretionary
Fiscal year
FY2028

Typical awards for this program (SAM.gov listing for ALN 93.213, not this notice): For Fiscal Years 2022 - 2023 (as of 7/20/2023), the total costs (which is the sum of the direct costs plus the facilities & administration costs) for competing grants ranged from a low of $28,500 to a high of $2,439,270. For this same time period, the average, total costs for competing grants varied based on "budget mechanism", as follows: Research Projects: $428,092 Cooperative Agreements: $1,115,156 Conference Grants: $36,180 Individual Fellowships: $45,712 Career Development: $35,992 Institutional Training: $419,354 Small Business (SBIR/STTR): $393,304

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public colleges & universities
  • Federally recognized tribal governments
  • Public & Indian housing authorities
  • Native American tribal organizations
  • 501(c)(3) nonprofits
  • Nonprofits without 501(c)(3) status
  • Private colleges & universities
  • For-profit organizations (not small businesses)
  • Small businesses
  • Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The National Institutes of Health intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose feasibility studies that could inform the design and conduct of subsequent definitive clinical trials (e.g., efficacy, effectiveness, pragmatic, dissemination and implementation, phase/stage II or later trials). Applications to this NOFO should demonstrate that the proposed feasibility research is scientifically necessary to design or plan the subsequent definitive clinical trial. Studies may utilize mixed methods and feasibility clinical trials to assess feasibility of recruitment, randomization, retention, intervention delivery, data collection, adherence, acceptability, and/or develop or adapt intervention components or protocols. The proposed feasibility research should enhance the rigor and reproducibility of the future trial methods. The subsequent definitive clinical trial should have the potential to make a significant impact on public health.

Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise in clinical trial planning, design, implementation, intervention development, and/or stakeholder engagement are encouraged to begin to consider applying for this new NOFO.

How to apply

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Assistance Listing

What is an ALN?

Reported obligations under ALN 93.213

Historical data · not a prediction
FY24$240M
FY25$233M
FY26$2.66M est.
Source: SAM.gov Assistance Listing 93.213. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.213

Historical data · not a prediction

Since October 1, 2023, 773 grant awards had funding actions under Research and Training in Complementary and Integrative Health, with 654 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.

  1. UNIVERSITY OF CALIFORNIA, SAN DIEGO$14.3M
  2. THE GENERAL HOSPITAL CORPORATION$12.3M
  3. YALE UNIV$11.6M
  4. UNIVERSITY OF CALIFORNIA IRVINE$9.18M
  5. UNIVERSITY OF UTAH$8.61M
Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

NCCIH Division of Extramural Research Program Officer
NCCIHDERFunding@nih.gov
Please contact via e-mail

Quick answers

Is “Feasibility Studies to Inform the Design of Future Clinical Trials” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around November 24, 2026. Forecast details and dates can change.

Who is eligible to apply for “Feasibility Studies to Inform the Design of Future Clinical Trials”?

The official notice names these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How do I apply for “Feasibility Studies to Inform the Design of Future Clinical Trials”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-28-011), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.