OpenResearch announcementOpportunity RFA-AI-27-005

Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)

National Institutes of Health · Department of Health and Human Services

At a glance

Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required) is an open federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due November 10, 2026. Total estimated funding is $18M across about 1 awards. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.855 (Allergy and Infectious Diseases Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Sep 1, 2026Posted
Nov 10, 2026Application deadlinenext date
Jul 1, 2027 (est.)Est. award date
Jan 9, 2027Archived

Posted: Sep 1, 2026
Close date: Nov 10, 2026
Archive date: Jan 9, 2027
Est. award date: Jul 1, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $18,000,000
Implied average award: $18,000,000 calculated
Expected awards: 1
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary

Typical awards for this program (SAM.gov listing for ALN 93.855, not this notice): from $2,500 to $6,395,901 and the average $426,165.

Implied average = estimated total funding ÷ expected number of awards, calculated by GrantsJunction. Actual awards vary.

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The purpose of this notice of funding opportunity (NOFO) is to support a Clinical Research Network (CRN) on Antimicrobial Resistance (AMR). The program aims to design, implement, and manage clinical research that addresses pivotal clinical questions related to AMR through a coordinated and integrated CRN. The CRN will comprise four centers: the Scientific Leadership Center (SLC), the Clinical Operations Center (COC), the Laboratory Center (LC), and the Statistics and Data Coordination Center (SDCC).

Full announcement & documents

The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.

RFA-AI-27-005-Full-Announcement.htmlFull Announcement · RFA-AI-27-005-Full-Announcement.htmlHTML · 157 KB

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Open the application packageUse opportunity number RFA-AI-27-005 on Grants.gov (Grants.gov Workspace). Open ↗
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyNational Institutes of Health · AMRClinicalResearchNetworkContact@mail.nih.gov Open ↗
Submit before November 10, 2026Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.855Allergy and Infectious Diseases ResearchProgram →

Reported obligations under ALN 93.855

Historical data · not a prediction

FY24

$4.07B

FY25

$4.38B

FY26

$4.3B est.

Source: SAM.gov Assistance Listing 93.855. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.855

Historical data · not a prediction

Since October 1, 2023, 15,420 grant awards had funding actions under Allergy and Infectious Diseases Research, with 10,548 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.

THE JOHNS HOPKINS UNIVERSITY$430M
FRED HUTCHINSON CANCER CENTER$420M
REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE$407M
DUKE UNIVERSITY$352M
WASHINGTON UNIVERSITY, THE$346M

Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

National Institutes of Health
AMRClinicalResearchNetworkContact@mail.nih.gov
301-402-2541

Quick answers

When is the deadline for “Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)”?

According to the official notice, applications are due November 10, 2026. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for “Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)”?

The official notice names these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through “Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)”?

Per the notice, total estimated program funding is $18,000,000 and the agency expects to make about 1 awards.

How do I apply for “Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-AI-27-005), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

OpenResearchALN 93.855