Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services
At a glance
Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due October 15, 2026. Total estimated funding is $3M across about 6 awards. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.242 (Mental Health Research Grants).
Summary assembled from the official notice's fields. The official notice governs.
Key facts
- May 28, 2026Posted
- Oct 15, 2026Application deadlinenext date
- Jul 1, 2026 (est.)Est. award date
- Dec 14, 2026Archived
- Posted
- May 28, 2026
- Close date
- Oct 15, 2026
- Archive date
- Dec 14, 2026
- Est. award date
- Jul 1, 2026
- Award floor
- Not specified
- Award ceiling
- Not specified
- Est. total funding
- $3,000,000
- Implied average award
- $500,000 calculated
- Expected awards
- 6
- Cost sharing
- Not required
- Funding instrument
- Grant
- Opportunity category
- Discretionary
Typical awards for this program (SAM.gov listing for ALN 93.242, not this notice): FY 2023 range: $1 to $17,379,729 Average Cost: $508,267
Implied average = estimated total funding ÷ expected number of awards, calculated by GrantsJunction. Actual awards vary.
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public colleges & universities
- Federally recognized tribal governments
- Public & Indian housing authorities
- Native American tribal organizations
- 501(c)(3) nonprofits
- Nonprofits without 501(c)(3) status
- Private colleges & universities
- For-profit organizations (not small businesses)
- Small businesses
- Others (see notice)
Additional information on eligibility (from the notice)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
A quick check against the listed applicant types — other requirements in the notice still apply.
Based on the published notice. Review the official notice for complete eligibility requirements.
What it funds
Official synopsis as published by the agency, formatted for readability.
The purpose of this notice of funding opportunity (NOFO) is to foster research that will inform and support the optimization, delivery, sustainability, and effectiveness of empirically-supported practices for addressing the mental health needs of older adults with serious mental illness (SMI). To this end, NIMH seeks applications that propose work that is focused on practice-relevant questions and conducted within and/or across settings where older adults with SMI are likely to be identified as needing care (e.g., primary care and geriatric specialty clinics, assisted living and long-term care facilities, and community centers). Applications may propose research related to adapting, optimizing, and implementing efficacious treatment and services interventions and strategies to improve clinical and functional outcomes among aging populations; examining mutable factors that impact fair and impartial mental health care access, utilization, quality, and outcomes and may serve as targets for intervention development for older adults with SMI; and developing and testing innovative treatment and service interventions that address barriers to accessing quality mental health care. Projects may also focus on systems-level factors and approaches for addressing SMI and improving access to evidence-based interventions in later life, such as evaluation of health system policies and practices, interventions that facilitate care transitions and continuity across settings, and strategies to improve care linkages and coordination across systems.
Full announcement & documents
The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.
How to apply
0 of 8 done · progress saved in this browser
Assistance Listing
What is an ALN?Reported obligations under ALN 93.242
Historical data · not a predictionAgency contact (as published)
National Institutes of Health
NIMH.DSIR.inquiries@mail.nih.gov
301-402-2541
Quick answers
When is the deadline for this opportunity?
According to the official notice, applications are due October 15, 2026. Confirm the deadline and submission time on Grants.gov before applying.
Who is eligible to apply for this opportunity?
The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.
How much funding is available through this opportunity?
Per the notice, total estimated program funding is $3,000,000 and the agency expects to make about 6 awards.
How do I apply for this opportunity?
Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-MH-27-180), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.
Related open opportunities
Matched on shared Assistance Listings, agency, categories and eligible applicant types.
Research on System Support and Tools for Provider Training and Quality Monitoring for Suicide Preventive Care
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Oct 17, 2025 (est.)
- Who can apply
- State governments, County governments, Independent school districts and 8 more
NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH BRAINS) (R01 Clinical Trial Optional)
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Oct 20, 2025 (est.)
- Who can apply
- State governments, County governments, Independent school districts and 8 more
Pilot Effectiveness Trials of Peer Support Services for Suicide Prevention
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Oct 28, 2025 (est.)
- Who can apply
- State governments, County governments, Independent school districts and 8 more
Establishing Pediatric CNS Pharmacodynamic Measures as Tools to Enable Psychiatric Indications in Adolescents
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Feb 13, 2026 (est.)
- Who can apply
- State governments, County governments, City or township governments and 12 more
Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Oct 11, 2026
- Who can apply
- State governments, County governments, City or township governments and 12 more
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Oct 22, 2026
- Who can apply
- State governments, County governments, City or township governments and 12 more