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ForecastedResearch announcementOpportunity RFA-OH-27-054

World Trade Center Youth Research Coordinating Center (U54)

Centers for Disease Control and Prevention - ERA · Department of Health and Human Services

At a glance

World Trade Center Youth Research Coordinating Center (U54) is a forecasted federal cooperative agreement opportunity from the Centers for Disease Control and Prevention - ERA (Department of Health and Human Services). The agency's forecast estimates an application due date of February 23, 2027; forecast dates can change. Individual awards are listed as up to $10M, with about 1 award expected and $50M in total estimated funding. The notice is unrestricted by applicant type, subject to any clarifications in the notice. Cost sharing is not required. It is funded under Assistance Listing 93.262 (Occupational Safety and Health Program).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

  1. Jul 31, 2026Forecast posted
  2. Nov 24, 2026 (est.)Full notice expectednext date
  3. Feb 23, 2027 (est.)Application deadline
  4. Jun 26, 2027 (est.)Est. award date
Posted
Jul 31, 2026
Est. close date
Feb 23, 2027
Est. award date
Jun 26, 2027
Award floor
Not specified
Award ceiling
$10,000,000
Est. total funding
$50,000,000
Expected awards
1
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Opportunity category
Mandatory
Fiscal year
FY2027

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public colleges & universities
  • Federally recognized tribal governments
  • Public & Indian housing authorities
  • Native American tribal organizations
  • 501(c)(3) nonprofits
  • Nonprofits without 501(c)(3) status
  • Private colleges & universities
  • For-profit organizations (not small businesses)
  • Small businesses
  • Unrestricted (any entity type)

Additional information on eligibility (from the notice)

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Applicants may not include foreign components, as defined in the HHS Grants Policy Statement. Applicants may include collaborators or consultants from foreign institutions.

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The National Institute for Occupational Safety and Health (NIOSH), World Trade Center (WTC) Health Program, plans to establish a WTC Youth Research Coordinating Center ("Center") through a U54 cooperative agreement.

In December 2022, Congress amended the Public Health Service Act (42 U.S.C. § 300mm–51(c)) to direct the WTC Health Program Administrator to establish a research cohort for emerging health impacts on youth. The cohort must be of sufficient size to support future research studies on the health and educational impacts of exposures resulting from the September 11, 2001, terrorist attacks (9/11).

The overall purpose of the Center is to:

  • Establish and maintain a WTC Youth Research Cohort of individuals who were: 
    • 21 years of age or younger at the time of 9/11 exposure, including those exposed in utero.
    • Within a certain distance of the WTC site on and after 9/11.
  • Develop and implement research on the long-term health and educational (including developmental and cognitive) impacts of individuals exposed at a young age to 9/11.

The Center will integrate multidisciplinary expertise in epidemiology, environmental and occupational health, information technology and data management, community-engaged recruitment and research, and related disciplines. Community engagement and effective stakeholder communication will be central to all Center activities.

The Center will support four functional core activities:

  1. Planning, Administration, and Evaluation.
  2. Information Technology (IT) and Data Management.
  3. Communication, Outreach, and Community Engagement.
  4. Research and Related Activities.

The expected public health impact includes addressing gaps in knowledge about the health and educational impacts associated with 9/11 among individuals exposed in utero or at a young age. It also includes improving understanding of the long-term effects of 9/11 exposures across the lifespan.

How to apply

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Assistance Listing

What is an ALN?

Reported obligations under ALN 93.262

Historical data · not a prediction
FY24$131M
FY25$128M
FY26$113M est.
Source: SAM.gov Assistance Listing 93.262. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

James Yiin, PhD, Scientific Program Official
jcy5@cdc.gov
513-841-4271

Quick answers

Is “World Trade Center Youth Research Coordinating Center (U54)” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around November 24, 2026. Forecast details and dates can change.

Who is eligible to apply for “World Trade Center Youth Research Coordinating Center (U54)”?

The notice lists eligibility as unrestricted — open to any type of entity — subject to clarifications in the notice's additional eligibility information.

How much funding is available through “World Trade Center Youth Research Coordinating Center (U54)”?

Per the notice, individual awards are listed as up to $10m, total estimated program funding is $50,000,000 and the agency expects to make about 1 awards.

How do I apply for “World Trade Center Youth Research Coordinating Center (U54)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-OH-27-054), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.