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ForecastedOpportunity RFA-TS-27-018

Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)

Centers for Disease Control and Prevention - ERA · Department of Health and Human Services

At a glance

Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) is a forecasted federal cooperative agreement opportunity from the Centers for Disease Control and Prevention - ERA (Department of Health and Human Services). The agency's forecast estimates an application due date of December 1, 2026; forecast dates can change. Individual awards are listed as up to $500K, with about 3 awards expected and $4.5M in total estimated funding. The notice is unrestricted by applicant type, subject to any clarifications in the notice. Cost sharing is not required. It is funded under Assistance Listing 93.061 (Innovations in Applied Public Health Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

  1. Jul 8, 2026Forecast posted
  2. Oct 1, 2026 (est.)Full notice expected
  3. Dec 1, 2026 (est.)Application deadlinenext date
  4. Aug 29, 2027 (est.)Est. award date
Posted
Jul 8, 2026
Est. close date
Dec 1, 2026
Est. award date
Aug 29, 2027
Award floor
Not specified
Award ceiling
$500,000
Est. total funding
$4,500,000
Expected awards
3
Cost sharing
Not required
Funding instrument
Cooperative Agreement
Opportunity category
Discretionary
Fiscal year
FY2027

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public colleges & universities
  • Federally recognized tribal governments
  • Public & Indian housing authorities
  • Native American tribal organizations
  • 501(c)(3) nonprofits
  • Nonprofits without 501(c)(3) status
  • Private colleges & universities
  • Others (see notice)
  • Unrestricted (any entity type)

Additional information on eligibility (from the notice)

Additional Eligibility Information to be included in the NOFO.

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.  

How to apply

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Assistance Listing

What is an ALN?

Reported obligations under ALN 93.061

Historical data · not a prediction
FY24$1.78M
FY25$2.91M
FY26$2.91M est.
Source: SAM.gov Assistance Listing 93.061. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

Dr. Candis Hunter
ncipc_erpo@cdc.gov
770-488-1347

Quick answers

Is “Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around October 1, 2026. Forecast details and dates can change.

Who is eligible to apply for “Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)”?

The notice lists eligibility as unrestricted — open to any type of entity — subject to clarifications in the notice's additional eligibility information.

How much funding is available through “Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)”?

Per the notice, individual awards are listed as up to $500k, total estimated program funding is $4,500,000 and the agency expects to make about 3 awards.

How do I apply for “Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-TS-27-018), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.