New Partners Initiative Translational HIV Research for Innovative Vaccines Ecosystem (NPI THRIVE)
At a glance
New Partners Initiative Translational HIV Research for Innovative Vaccines Ecosystem (NPI THRIVE) is a closed federal cooperative agreement opportunity from the Agency for International Development. The application deadline was January 28, 2025. Individual awards are listed as $98.5M. Applicant types listed as eligible include 501(c)(3) nonprofits. Cost sharing is not required. It is funded under Assistance Listing 98.001 (USAID Foreign Assistance for Programs Overseas).
Summary assembled from the official notice's fields. The official notice governs.
Key facts
- Dec 18, 2024Posted
- Jan 28, 2025Application deadline
- Posted
- Dec 18, 2024
- Close date
- Jan 28, 2025
- Award floor
- $98,500,000
- Award ceiling
- $98,500,000
- Est. total funding
- Not specified
- Expected awards
- Not specified
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Opportunity category
- Discretionary
Who can apply
- 501(c)(3) nonprofits
A quick check against the listed applicant types — other requirements in the notice still apply.
Based on the published notice. Review the official notice for complete eligibility requirements.
What it funds
Official synopsis as published by the agency, formatted for readability.
The United States Agency for International Development (USAID) is seeking applications for cooperative agreements from qualified entities to implement activities under the Translational HIV Research for Innovative Vaccines Ecosystem (NPI THRIVE) Program. NPI-THRIVE is a New Partnerships Initiative (NPI) Activity, meaning it encourages the use of innovative, locally-led approaches with new, nontraditional, and local partners. Eligibility for these awards is not restricted. The overall goal of NPI THRIVE is to accelerate the development of a safe and globally effective HIV vaccine by supporting a collaborative research ecosystem led by scientists and institutions from countries in Africa with high burdens of HIV working in close partnership with leading scientific institutions from other regions. This will be achieved through pursuing two complementary objectives, one focusing on clinical research and the other on preclinical research.
USAID intends to award at least two Applicants, at least one for each of the two objectives of this funding opportunity, based on the merit review criteria described in this NOFO and subject to a risk assessment. Parties interested in applying are encouraged to read this NOFO thoroughly to understand the type of program sought, application submission requirements, and selection process. This funding opportunity is posted on www.grants.gov, and may be amended. It is the Applicant's responsibility to regularly check the website to ensure they have the latest information pertaining to this NOFO and to ensure that the NOFO has been received from the internet in its entirety. USAID bears no responsibility for data errors resulting from transmission or conversion processes. If you have difficulty registering on www.grants.gov or accessing the NOFO, please contact the Grants.gov Helpdesk at 1-800-518-4726 or via email at support@grants.gov for technical assistance.
Full announcement & documents
The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.
Assistance Listing
What is an ALN?Reported obligations under ALN 98.001
Historical data · not a predictionAgency contact (as published)
Koni Demissie Grantor
npithrive@usaid.gov
2025674997
Quick answers
Who is eligible to apply for this opportunity?
The official notice names these applicant types as eligible: 501(c)(3) nonprofits. Additional restrictions may apply; review the full notice.
How much funding is available through this opportunity?
Per the notice, individual awards are listed as $98.5m.
How do I apply for this opportunity?
Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity 7200AA25RFA00001), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.
Related open opportunities
Matched on shared Assistance Listings, agency, categories and eligible applicant types.
Limited Competition: International epidemiology Databases to Evaluate AIDS (IeDEA) (U01 Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Dec 3, 2025 (est.)
- Who can apply
- Public colleges & universities, 501(c)(3) nonprofits, Private colleges & universities and 1 more
Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Cerebroprotection – Network Sites and Coordinating Center (U01- CT Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Mar 18, 2026 (est.)
- Who can apply
- State governments, County governments, City or township governments and 12 more
Notice of Intent to Publish a Funding Opportunity Announcement for HIV Pediatric, Adolescent and Maternal Clinical Trials
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Mar 25, 2026 (est.)
- Who can apply
- State governments, County governments, Independent school districts and 8 more
Translational Center for Accelerating the Use of Digital Health Technologies Data in AD/ADRD Research
National Institutes of Health- Award range
- Amount not specified
- Est. close
- May 25, 2026 (est.)
- Who can apply
- State governments, County governments, City or township governments and 12 more
Centers for AIDS Research (CFAR)
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Aug 19, 2026 (est.)
- Who can apply
- State governments, County governments, City or township governments and 12 more
Martin Delaney Collaboratories for HIV Cure Research
National Institutes of Health- Award range
- Amount not specified
- Est. close
- Aug 19, 2026 (est.)
- Who can apply
- State governments, County governments, Independent school districts and 8 more