Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services
At a glance
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due January 7, 2027. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.113 (Environmental Health) and 10 other listings.
Summary assembled from the official notice's fields. The official notice governs.
Key facts
- Jan 22, 2025Posted
- Jan 7, 2027Application deadlinenext date
- Feb 6, 2027Archived
- Posted
- Jan 22, 2025
- Close date
- Jan 7, 2027
- Archive date
- Feb 6, 2027
- Award floor
- Not specified
- Award ceiling
- Not specified
- Est. total funding
- Not specified
- Expected awards
- Not specified
- Cost sharing
- Not required
- Funding instrument
- Grant
- Opportunity category
- Discretionary
Typical awards for this program (SAM.gov listing for ALN 93.113, not this notice): Range: $2,500 to $6,747,780 Average: $444,487
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public colleges & universities
- Federally recognized tribal governments
- Public & Indian housing authorities
- Native American tribal organizations
- 501(c)(3) nonprofits
- Nonprofits without 501(c)(3) status
- Private colleges & universities
- For-profit organizations (not small businesses)
- Small businesses
- Others (see notice)
Additional information on eligibility (from the notice)
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
A quick check against the listed applicant types — other requirements in the notice still apply.
Based on the published notice. Review the official notice for complete eligibility requirements.
What it funds
Official synopsis as published by the agency, formatted for readability.
The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions. Existing data suggest that significant acute and chronic disease inequities exist for NA populations. Concurrently, NA populations experience unique sociopolitical, historical, and environmental stressors and risks that may exacerbate health conditions and/or impact the effectiveness of existing solutions to address the conditions. They also possess unique strengths and resiliencies that can mitigate stressors or inform intervention strategies. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to test science-based, culturally appropriate solutions to reduce morbidity and mortality through identification and remediation of precursors to diseases and disorders and through culturally informed treatment. Interventions should be designed with a consideration for sustainability within the communities where they are tested, and have the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate. For the purposes of this NOFO, NA includes the following populations: Alaska Natives, American Indians (whose ancestral lands fall at least partially within the U.S. main land).
Full announcement & documents
The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.
How to apply
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Assistance Listings
What is an ALN?- 93.113Environmental HealthProgram →
- 93.121Oral Diseases and Disorders ResearchProgram →
- 93.213Research and Training in Complementary and Integrative HealthProgram →
- 93.242Mental Health Research GrantsProgram →
- 93.273Alcohol Research ProgramsProgram →
- 93.279Drug Use and Addiction Research ProgramsProgram →
- 93.310Trans-NIH Research SupportProgram →
- 93.313NIH Office of Research on Women's HealthProgram →
- 93.361Nursing ResearchProgram →
- 93.865Child Health and Human Development Extramural ResearchProgram →
- 93.866Aging ResearchProgram →
Reported obligations under ALN 93.113
Historical data · not a predictionWho was funded under ALN 93.113
Historical data · not a predictionSince October 1, 2023, 2,194 grant awards had funding actions under Environmental Health, with 1,535 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI$58.1M
- EMORY UNIVERSITY$45.3M
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK$42.7M
- UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL$41.1M
- NEW YORK UNIVERSITY$39.8M
Agency contact (as published)
National Institutes of Health
grantsinfo@nih.gov
301-402-2541
Places named in the notice
Derived from the notice text. A place being named does not by itself restrict eligibility.
Quick answers
When is the deadline for “Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)”?
According to the official notice, applications are due January 7, 2027. Confirm the deadline and submission time on Grants.gov before applying.
Who is eligible to apply for “Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)”?
The official notice names these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.
How do I apply for “Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)”?
Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-25-378), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.
Related open opportunities
Matched on shared Assistance Listings, agency, categories and eligible applicant types.
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 7, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 4, 2028
- Who can apply
- State governments, County governments, City or township governments and 12 more
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 7, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 7, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 7, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
National Institutes of Health- Award range
- Amount not specified
- Closes
- May 8, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more