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OpenResearch announcementOpportunity PAR-27-021

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services

At a glance

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due July 1, 2028. Individual awards are listed as $50K – $400K. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.310 (Trans-NIH Research Support) and 3 other listings.

Summary assembled from the official notice's fields. The official notice governs.

Key facts

  1. Jun 25, 2026Posted
  2. Jul 1, 2028Application deadlinenext date
  3. May 1, 2027 (est.)Est. award date
  4. Sep 1, 2028Archived
Posted
Jun 25, 2026
Close date
Jul 1, 2028
Archive date
Sep 1, 2028
Est. award date
May 1, 2027
Award floor
$50,000
Award ceiling
$400,000
Est. total funding
Not specified
Expected awards
Not specified
Cost sharing
Not required
Funding instrument
Grant
Opportunity category
Discretionary

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public colleges & universities
  • Federally recognized tribal governments
  • Public & Indian housing authorities
  • Native American tribal organizations
  • 501(c)(3) nonprofits
  • Nonprofits without 501(c)(3) status
  • Private colleges & universities
  • For-profit organizations (not small businesses)
  • Small businesses
  • Others (see notice)

Additional information on eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.

Full announcement & documents

The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.

How to apply

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Assistance Listings

What is an ALN?

Reported obligations under ALN 93.310

Historical data · not a prediction
FY24$1.17B
FY25$1.06B
FY26$28.1M est.
Source: SAM.gov Assistance Listing 93.310. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

National Institutes of Health
odsig@mail.nih.gov
301-402-2541

Quick answers

When is the deadline for “Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)”?

According to the official notice, applications are due July 1, 2028. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for “Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)”?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through “Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)”?

Per the notice, individual awards are listed as $50k – $400k.

How do I apply for “Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-27-021), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.