ForecastedResearch announcementOpportunity PAR-28-007

The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network

National Institutes of Health · Department of Health and Human Services

At a glance

The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network is a forecasted federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of January 25, 2027; forecast dates can change. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.350 (National Center for Advancing Translational Sciences).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Jul 20, 2026Forecast posted
Sep 1, 2026 (est.)Full notice expected
Jan 25, 2027 (est.)Application deadlinenext date
Dec 15, 2027 (est.)Est. award date

Posted: Jul 20, 2026
Est. close date: Jan 25, 2027
Est. award date: Dec 15, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: Not specified
Expected awards: Not specified
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2028

Typical awards for this program (SAM.gov listing for ALN 93.350, not this notice): NCATS Assistance: $1 - $11,215,948, average: $1,718,935

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The Clinical and Translational Science Awards Program Trial Innovation Network (TIN) is a collaborative initiative aimed at addressing critical roadblocks in the design and implementation of multi-center clinical trials. The goal of the TIN is to execute trials better, faster, and more cost-efficiently, as well as serve as a national laboratory to study, understand, and innovate the process of conducting multi-center clinical trials. The purpose of the issuance of the Next Generation of the TIN Notice of Funding Opportunity (NOFO) is to advance the science of clinical trials by developing and implementing innovative solutions to address challenges at the clinical trial and trial network levels. Topics of interest include, but are not limited to, safety monitoring tools and resources, trial leader training and mentorship, digital health technologies, genomic capacity, and disease progression modeling.

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

This is a Forecast that will invite applications from all eligible organizations to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered for funding.

How to apply

0 of 8 done · progress saved in this browser

Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Watch for the full noticeThe agency estimates posting it around September 1, 2026. Save this grant to track changes.
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyDivision of Clinical Innovation, NCATS · tin@nih.gov Open ↗
Submit before January 25, 2027Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.350National Center for Advancing Translational SciencesProgram →

Reported obligations under ALN 93.350

Historical data · not a prediction

FY24

$596M

FY25

$626M

FY26

— est.

Source: SAM.gov Assistance Listing 93.350. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

Division of Clinical Innovation, NCATS
tin@nih.gov
Please contact via e-mail.

Quick answers

Is this opportunity open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around September 1, 2026. Forecast details and dates can change.

Who is eligible to apply for this opportunity?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How do I apply for this opportunity?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-28-007), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedResearchALN 93.350