ForecastedResearch announcementOpportunity RFA-DK-28-114

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

National Institutes of Health · Department of Health and Human Services

At a glance

NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional) is a forecasted federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of January 28, 2027; forecast dates can change. Total estimated funding is $9M across about 7 awards. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Jul 1, 2026Forecast posted
Nov 28, 2026 (est.)Full notice expectednext date
Jan 28, 2027 (est.)Application deadline
Nov 1, 2027 (est.)Est. award date

Posted: Jul 1, 2026
Est. close date: Jan 28, 2027
Est. award date: Nov 1, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $9,000,000
Implied average award: $1,285,714 calculated
Expected awards: 7
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2028

Typical awards for this program (SAM.gov listing for ALN 93.847, not this notice): Project Grants: Range of $1,300 to $10,834,000; $418,000 average NRSAs: Range of $2,500 to $869,000; $116,000 average SBIR: Range of $6,500 to $2,074,000; $585,000 average

Implied average = estimated total funding ÷ expected number of awards, calculated by GrantsJunction. Actual awards vary.

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This Notice of Funding Opportunity (NOFO) announcement invites applications for NIDDK Multi-Purpose Resource-Related Research, Multi-Component Centers Cooperative Agreement (U2C - Clinical Trial Not Allowed). To help increase rigor, reproducibility and cost efficiencies, U2C centers offer highly specialized cores that provide a range of topic focused services including but not limited to hands-on technical services, consulting, research/data coordination, or other research support services provided by nationally recognized experts. In contrast to other types of Core Centers, the U2C services should be largely provided to clients located at another institution where the needed service or expertise is not available. Provided services enable high impact research within NIDDK’s research mission including but not limited to integrative physiology, metabolic phenotyping, nutrition, community engagement, communications, and/or data and research coordination. The disease focus should similarly be within NIDDK’s mission, such as obesity and diabetes. The clients for these services can be a consortia, research partners or individual investigators and should offer experiential training in at least one of the provided services. Applications to this NOFO can propose optional opportunities and/or a pilot and feasibility grant program depending on the needs of the program.

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Watch for the full noticeThe agency estimates posting it around November 28, 2026. Save this grant to track changes.
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyDivision of Diabetes, Endocrinology and Metabolic Diseases · NIDDK_DEM@nih.gov Open ↗
Submit before January 28, 2027Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.847Diabetes, Digestive, and Kidney Diseases Extramural ResearchProgram →

Reported obligations under ALN 93.847

Historical data · not a prediction

FY24

$1.97B

FY25

$2.04B

FY26

$111M est.

Source: SAM.gov Assistance Listing 93.847. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

Division of Diabetes, Endocrinology and Metabolic Diseases
NIDDK_DEM@nih.gov
NIDDK_DEM@nih.gov

Quick answers

Is this opportunity open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around November 28, 2026. Forecast details and dates can change.

Who is eligible to apply for this opportunity?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through this opportunity?

Per the notice, total estimated program funding is $9,000,000 and the agency expects to make about 7 awards.

How do I apply for this opportunity?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-DK-28-114), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedResearchALN 93.847