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Assistance Listing 93.110

Special Projects of Regional and National Significance

Department of Health and Human Services · Health Resources and Services Administration

Assistance Listing 93.110, “Special Projects of Regional and National Significance,” is a federal program administered by Department of Health and Human Services. It provides cooperative agreement and grant assistance. GrantsJunction currently tracks 0 open, 10 forecasted and 52 closed opportunities under this listing. The agency reported $266M in obligations for fiscal year 2025.

Program objective

The Special Projects of Regional and National Significance Program (SPRANS) carries out maternal and child health (MCH) projects to support training and research; oral health integration; genetic disease testing, counseling, and information development and dissemination programs; newborn screening for sickle cell anemia and other genetic disorders; and comprehensive hemophilia diagnostic and treatment centers. The Supporting Fetal Alcohol Spectrum Disorder (FASD) Screening and Intervention helps reduce alcohol use during pregnancy and improves outcomes for children with FASD nationwide, especially in communities where there is a high rate of binge drinking during pregnancy, including rural areas and medically underserved communities. The program focuses on educating primary care providers and increasing the use of screening, intervention, and referral processes for high-risk pregnancies. The State Maternal Health Innovation program creates state-led maternal health task forces to bring together the voices of key leaders, and pregnant and postpartum individuals using state-specific maternal health data to develop and implement innovative approaches to address the most pressing maternal health needs and disparities. State approaches include strengthening partnerships and collaborations, improving state-level data surveillance on maternal mortality and severe maternal morbidity, and promoting and executing innovation in maternal health service delivery. The MCH Research Portfolio includes the MCH Research Consortium, Maternal Health Research Collaborative for Minority-Serving Institutions, MCH Research Network, and MCH Field-Initiated Innovative Research Studies programs. The research portfolio advances maternal and child health by generating and testing innovative, real-world approaches to improve population-level outcomes. The program addresses critical evidence gaps through the development of research infrastructure and the conduct of rigorous, community-engaged research in close partnership with families and other stakeholders. MCH RNs focus on collaborative, interdisciplinary. The Children’s Safety Network (CSN) purpose is to increase the capacity of Title V agencies to adopt and implement evidence-based child and adolescent safety programs, practices, and policies, with a specific focus on injury and violence-related to Title V performance and outcome measures, such as injury hospitalizations, bullying, safe sleep, and suicide, as well as leading causes of injury-related deaths among children and adolescents (e.g., motor vehicle crashes, firearms, and poisonings).

As published in the SAM.gov Assistance Listing.

Current opportunities under 93.110

ForecastedALN 93.110

Leadership Education in Adolescent Health (LEAH)

Health Resources and Services Administration
Award range
$400K – $459K
Est. close
Jan 20, 2027 (est.)
Who can apply
Public colleges & universities and Others (see notice)
Source: Grants.govVerified today
ForecastedALN 93.110

Fetal, Infant, and Child Death Review Program

Health Resources and Services Administration
Award range
$5.15M
Est. close
Jan 20, 2027 (est.)
Who can apply
State governments, County governments, City or township governments and 13 more
Source: Grants.govVerified today
ForecastedALN 93.110

Infant-Toddler Court Program–State Awards

Health Resources and Services Administration
Award range
$700K
Est. close
Apr 21, 2027 (est.)
Who can apply
State governments, County governments, City or township governments and 11 more
Source: Grants.govVerified today
ForecastedALN 93.110

Women's Initiative for Screening and Health (WISH)

Health Resources and Services Administration
Award range
Up to $1M
Est. close
Sep 20, 2026 (est.)
Who can apply
State governments, County governments, City or township governments and 11 more
Source: Grants.govVerified today

Eligible applicants (program level)

  • Other
  • Federally Recognized Indian/Native American/Alaska Native Tribal Government
  • Indian/Native American/Alaska Native Tribal Government (Other than Federally Recognized)
  • U.S. State Government (including the District of Columbia)
  • Local
  • Nonprofit Organization
  • U.S. Territory (or Possession) Government (including freely-associated states)

Training grants may be made to public or private nonprofit institutions of higher learning. Research grants may be made to public or private nonprofit institutions of higher learning and public or private nonprofit private agencies and organizations engaged in research or in MCH or Children with Special Health Care Needs (CSHCN) programs. Any public or private entity is eligible for hemophilia, genetics, and environmental health grants and other special project grants, including SPRANS and CISS. Eligible entities for the Supporting Fetal Alcohol Spectrum Disorders Screening and Intervention program are any domestic public or private entity, including Indian tribes or tribal organizations (as those terms are defined at 25 U.S.C. 450b). See 42 CFR § 51a.3(a), and domestic faith-based and community-based organizations. Eligible entities for the State Maternal Health Innovation program include any domestic public or private entity, including Indian tribes or tribal organizations, as well as domestic faith-based and community-based organizations. Eligible entities for the Integrated Maternal Health Services program include any domestic public or private entity, including Indian tribes or tribal organizations, as well as domestic faith-based and community-based organizations.

Intended beneficiaries: Young Child (4-9), Other, Infant and Toddler (0-3) and Health Professional.

Program-level eligibility from SAM.gov. Each funding notice sets its own requirements.

Reported obligations by fiscal year

Historical data · not a prediction
FY24$274M
FY25$266M
FY26$186M est.

Range and average of financial assistance (from the listing): (Project Grants) FY 23: act. $27,562 to $547,250; $206,451 FY 24: est. $12,910 to $547,250; $208,087 FY 25: est. $26,341 to $536,769; $208,376 (Project Cooperative Agreements) FY 23: act. $75,000 to $11,150,000; $1,053,622 FY 24 est. $75,000 to $11,282,998; $924,222 FY 25: est. $75,000 to $11,148,707; $982,349

Source: SAM.gov Assistance Listing 93.110. Hatched bars are agency estimates. These totals do not indicate approval rates.

Recently closed under 93.110

Closed opportunities under 93.110
OpportunityStatusAward rangeClosesALN
Transforming Pediatrics for Early Childhood (TPEC) ProgramHealth Resources and Services Administration
ClosedUp to $950KJul 10, 202693.110
Maternal and Child Health Research Consortium (MCH RC)Health Resources and Services Administration
ClosedAmount not specifiedApr 23, 202593.110
Healthy Tomorrows Partnership for Children Program (HTPCP)Health Resources and Services Administration
ClosedUp to $75KMar 17, 202593.110
Pediatric Pulmonary Centers ProgramHealth Resources and Services Administration
ClosedUp to $340KFeb 18, 202593.110
ClosedUp to $367KJan 27, 202593.110
Maternal and Child Health Public Health Catalyst ProgramHealth Resources and Services Administration
ClosedUp to $135KJan 23, 202593.110
ClosedAmount not specifiedJan 3, 202593.110
Center for Maternal and Child Health Medicaid PartnershipsHealth Resources and Services Administration
ClosedUp to $2MJul 10, 202493.110
Maternal and Child Health Policy Innovation ProgramHealth Resources and Services Administration
ClosedUp to $400KJul 10, 202493.110
ClosedUp to $950KJun 21, 202493.110

Frequently asked questions

What is ALN 93.110?

93.110 is the Assistance Listing Number for “Special Projects of Regional and National Significance.” Assistance Listing Numbers (formerly CFDA numbers) identify federal assistance programs; individual grant opportunities reference the listing they are funded under.

Who can apply under ALN 93.110?

The SAM.gov listing names these applicant types: Other, Federally Recognized Indian/Native American/Alaska Native Tribal Government, Indian/Native American/Alaska Native Tribal Government (Other than Federally Recognized), U.S. State Government (including the District of Columbia), Local, Nonprofit Organization and U.S. Territory (or Possession) Government (including freely-associated states). Each funding notice under the program sets its own eligibility, so check the specific opportunity.

How much funding does 93.110 provide?

The agency reported $265,688,703 in obligations for FY2025 in the SAM.gov Assistance Listing. These are program-wide totals reported by the agency, not a prediction of future awards.