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Assistance Listing 93.394

Cancer Detection and Diagnosis Research

Department of Health and Human Services · National Institutes of Health

Assistance Listing 93.394, “Cancer Detection and Diagnosis Research,” is a federal program administered by Department of Health and Human Services. It provides cooperative agreement and grant assistance. GrantsJunction currently tracks 39 open, 15 forecasted and 1 closed opportunities under this listing. The agency reported $602M in obligations for fiscal year 2025.

Program objective

To improve screening and early detection strategies and to develop accurate diagnostic techniques and methods for predicting the course of disease in cancer patients. Screening and Early Detection research includes development of strategies to decrease cancer mortality by finding tumors early when they are more amenable to treatment. Diagnosis research focuses on methods to determine the presence of a specific type of cancer; to predict its course and response to therapy, both a particular therapy or a class of agents; and to monitor the effect of the therapy and the appearance of disease recurrence. These methods include diagnostic imaging and direct analyses of specimens from tumor or other tissues. Support is also provided for establishing and maintaining resources of human tissue to facilitate research. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

As published in the SAM.gov Assistance Listing.

Current opportunities under 93.394

All 54 →

Eligible applicants (program level)

  • Local
  • Not-for-Profit Organization
  • Territorial
  • State
  • Small Business Person
  • Nonprofit Organization
  • International Organization
  • For-Profit Organization
  • Tribal

The awardee will be a university, college, hospital, public agency, nonprofit research institution or organization, unit of tribal government, or a for-profit organization that submits an application and receives a grant or cooperative agreement for support of research by a named principal investigator. SBIR grants can be awarded only to domestic small businesses (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed, and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees) which "partner" with a research institution in cooperative research and development. At least 40 percent of the project is to be performed by the small business concern and at least 30 percent by the research institution. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.

Intended beneficiaries: Private nonprofit institution/organization, Small business, Health Professional, Public nonprofit institution/organization, Scientist/Researchers, Other public institution/organization and Profit organization.

Program-level eligibility from SAM.gov. Each funding notice sets its own requirements.

Reported obligations by fiscal year

Historical data · not a prediction
FY24$541M
FY25$602M
FY26$717M est.

Range and average of financial assistance (from the listing): Range: $8,000 to $8,841,413 Average: $577,172

Source: SAM.gov Assistance Listing 93.394. Hatched bars are agency estimates. These totals do not indicate approval rates.

Recently closed under 93.394

Closed opportunities under 93.394
OpportunityStatusAward rangeClosesALN
ClosedUp to $499KSep 7, 202693.393, 93.394, 93.395, 93.396

Frequently asked questions

What is ALN 93.394?

93.394 is the Assistance Listing Number for “Cancer Detection and Diagnosis Research.” Assistance Listing Numbers (formerly CFDA numbers) identify federal assistance programs; individual grant opportunities reference the listing they are funded under.

Who can apply under ALN 93.394?

The SAM.gov listing names these applicant types: Local, Not-for-Profit Organization, Territorial, State, Small Business Person, Nonprofit Organization, International Organization, For-Profit Organization and Tribal. Each funding notice under the program sets its own eligibility, so check the specific opportunity.

How much funding does 93.394 provide?

The agency reported $602,293,691 in obligations for FY2025 in the SAM.gov Assistance Listing. These are program-wide totals reported by the agency, not a prediction of future awards.