Grantmaking public charity · EIN 04-3594491
Spastic Paraplegia Foundation Inc
O Fallon, MO
Spastic Paraplegia Foundation Inc is a public charity that makes grants based in O Fallon, MO. On its Form 990 (Schedule I) for tax year 2025, it reported $964K in grants paid across 5 grants, with $3.55M in total assets. Its largest grants went to Critical Path Institute, Drexel University and Columbia University.
How to request funding
Its Form 990 lists the grants it made but not how it chooses recipients. Check Spastic Paraplegia Foundation Inc's website or contact it to ask whether it considers requests.
How it makes and monitors grants (Schedule I, Part IV)
The Organization reviews and ranks every research grant proposal submitted according to their alignment with the mission of SPF. Awards are made based upon the availability of funds from donations. The Board of Directors also considers other proposals that will facilitate advocacy, therapies and open research. Awards of all types are generally paid in 5 installments. The first installment is paid upon receipt of a countersigned research grant agreement. The second through fourth installment payments are made upon receipt of an interim progress report describing the research conducted under the award to date. The fifth and final installment payment is made upon receipt of a final report of clinical findings and a financial report detailing how the grant funds were utilized.
Grants as reported on its Form 990 for tax year 2025; the application guidance above is general for this type of funder. Requirements change; confirm with the organization before applying.
Mission
1. To fund scientific research to discover the cures for hereditary spastic paraplegia and primary lateral sclerosis. 2. To provide information about the disorders to patients and their loved ones, and to the general public. 3. To provide emotional support to patients and their loved ones.
As stated on its Form 990.
Largest grants, tax year 2025
Historical data · not a prediction| Recipient | Location | Purpose | Amount |
|---|---|---|---|
| Critical Path Institute | Tucson, AZ | Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS) Taskforce to create a consortium between leading academic institutions, pharmaceutical i | $500,000 |
| Drexel University | Philadelphia, PA | Combination Therapy for HSP-SPG4: Repurposed FDA Drug, BpV-Mediated Regeneration, and Activity-Based Rehabilitation | $150,000 |
| Columbia University | New York, NY | Extension of Natural History Study of PLS | $149,957 |
| To Cure A Rose Foundation | Austin, TX | Frank Davis Amenability and Tool Box | $89,000 |
| Children's Hospital Corporation Grants Management Harvard University | Boston, MA | Bridge SP-CERN to fund the existing project until NIH funding was received | $75,000 |
Names and purposes as reported to the IRS.
Where its grants went
Quick answers
Does Spastic Paraplegia Foundation Inc accept grant applications?
Its Form 990 lists the grants it made but not how it chooses recipients. Check Spastic Paraplegia Foundation Inc's website or contact it to ask whether it considers requests. Form 990 does not report an application process, so confirm with the organization.
How much does Spastic Paraplegia Foundation Inc give each year?
For tax year 2025, it reported $963,957 in grants paid (5 grants). Giving can change from year to year.
What organizations has Spastic Paraplegia Foundation Inc funded?
Its largest grants in tax year 2025 went to Critical Path Institute (AZ), $500K, Drexel University (PA), $150K, Columbia University (NY), $150K, To Cure A Rose Foundation (TX), $89K and Children's Hospital Corporation Grants Management Harvard University (MA), $75K.