Countering Biological Weapons Threats
Bureau of International Security-Nonproliferation · Department of State
At a glance
Countering Biological Weapons Threats is a closed federal cooperative agreement opportunity from the Bureau of International Security-Nonproliferation (Department of State). The application deadline was July 30, 2025. Individual awards are listed as $250K – $5M, with about 10 awards expected and $15M in total estimated funding. Applicant types listed as eligible include others (see notice). Cost sharing is not required. It is funded under Assistance Listing 19.033 (Global Threat Reduction).
Summary assembled from the official notice's fields. The official notice governs.
Key facts
- May 30, 2025Posted
- Jul 30, 2025Application deadline
- Posted
- May 30, 2025
- Close date
- Jul 30, 2025
- Award floor
- $250,000
- Award ceiling
- $5,000,000
- Est. total funding
- $15,000,000
- Expected awards
- 10
- Cost sharing
- Not required
- Funding instrument
- Cooperative Agreement
- Opportunity category
- Discretionary
Who can apply
- Others (see notice)
Additional information on eligibility (from the notice)
The following organizations are eligible to apply: U.S. for-profit organizations or businesses; U.S.-based non-profit/non-governmental organizations with or without 501(c) (3) status of the U.S. tax code; U.S.-based private, public, or state institutions of higher education; foreign-based non-profit organizations/non-government organizations (NGO); Federally Funded Research and Development Centers (FFRDCs); Public International Organizations (PIO) ; Foreign Public Entities (FPE); and foreign-based institutions of higher education.
- Public colleges & universities
- 501(c)(3) nonprofits
- Nonprofits without 501(c)(3) status
- Private colleges & universities
- For-profit organizations (not small businesses)
A quick check against the listed applicant types — other requirements in the notice still apply.
Based on the published notice. Review the official notice for complete eligibility requirements.
What it funds
Official synopsis as published by the agency, formatted for readability.
ISN/CTR’s Biosecurity Engagement Program (BEP) advances the Trump Administration’s Executive Order (E.O.) on Improving the Safety and Security of Biological Research, which pledges to “balance the prevention of catastrophic consequences with maintaining readiness against biological threats and driving global leadership in biotechnology, biological countermeasures, biosecurity, and health research”. In alignment with this E.O., BEP engages partner countries to prevent U.S. adversaries from developing or using biological weapons (BW) against Americans. BEP also protects U.S. biotechnologies, sensitive data, and intellectual property (IP), and bolsters U.S. leadership of global biotechnology markets through private sector engagement to outcompete China, and promotes partner countries’ adoption of U.S. laboratory security, safety, and cybersecurity standards. To successfully achieve this mission, BEP partners include biological and biotechnology laboratories, bio- and data repositories, universities, science and technology organizations or academies, foreign government organizations and entities, biosafety associations or similar professional associations, and private industry. The expertise and tools acquired through BEP engagements are critical to enable our partners to counter the predatory and exploitative efforts of U.S. adversaries that threaten U.S. national and economic security.
Full announcement & documents
The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.
- CTR NOFO Q&AFull Announcement · CTR NOFO Q&A - Final posted 28 July.pdfPDF · 555 KB
- FY 2025 Budget TemplateFull Announcement · FY 2025 Budget Template 241004.xlsxVND. · 110 KB
- FY25 CTR Consolidated Project ListFull Announcement · FY25 CTR Consolidated Project List.xlsxVND. · 42 KB
- FY25 CTR Project Narrative TemplateFull Announcement · FY25 CTR Project Narrative Template 250708.docxVND. · 32 KB
- Monitoring Indicator Table SampleFull Announcement · Monitoring Indicator Table Sample.xlsxVND. · 21 KB
- NOFO GuidanceFull Announcement · BEP FY25 NOFO DFOP0017244 - 6 June 2025.docxVND. · 88 KB
Assistance Listing
What is an ALN?Reported obligations under ALN 19.033
Historical data · not a predictionAgency contact (as published)
Bureau of International Security-Nonproliferation
703-516-1684
Quick answers
Who is eligible to apply for “Countering Biological Weapons Threats”?
The official notice lists these applicant types as eligible: Others (see notice). Additional restrictions may apply; review the full notice.
How much funding is available through “Countering Biological Weapons Threats”?
Per the notice, individual awards are listed as $250k – $5m, total estimated program funding is $15,000,000 and the agency expects to make about 10 awards.
How do I apply for “Countering Biological Weapons Threats”?
Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity DFOP0017244), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.
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