OpenResearch announcementOpportunity PAR-25-357

NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services

At a glance

NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due October 16, 2027. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.867 (Vision Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Jan 2, 2025Posted
Oct 16, 2027Application deadlinenext date
Nov 21, 2027Archived

Posted: Jan 2, 2025
Close date: Oct 16, 2027
Archive date: Nov 21, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: Not specified
Expected awards: Not specified
Cost sharing: Not required
Funding instrument: Grant
Opportunity category: Discretionary

Typical awards for this program (SAM.gov listing for ALN 93.867, not this notice): FOR 2023: Research Grants (R): $12,400 to $2,178,277; Avg $422,981. Cooperative Agreements: $10,980 to $7,324,750; Avg $1,067,398. Centers (P): $400,718 to $949,680; Avg $677,851. K (Institutional): $183,986 to $545,160; Avg $454,904. K (Individual): $15,332 to $277,133; Avg $177,182. NRSA (Institutional): $28,815 to $272,894; Avg $142,678. NRSA (Individual): $2,500 to $78,552; Avg $47,548. SBIR Phase I: $54,475 to $350,075; Avg $270,429. SBIR Phase II: $245,829 to $1,907,135; Avg $768,574. STTR Phase I: $149,664 to $341,302; Avg $273,829. STTR Phase II: $289,895 to $537,483; Avg $402,459. SBIR/STTR Phase III: none. FOR 2024 YTD: Research Grants (R): $4,455 to $2,153,230; Avg $428,107. Cooperative Agreements: $81,518 to $8,942,823; Avg $1,283,922. Centers (P): $161,000 to $947,710; Avg $654,204. K (Institutional): $285,890 to $562,320; Avg $478,162. K (Individual): $21,767 to $280,704; Avg $175,903. NRSA (Institutional): $29,506 to $555,162; Avg $144,608. NRSA (Individual): $3,000 to $81,892; Avg $51,319. SBIR Phase I: $54,709 to $365,000; Avg $259,725. SBIR Phase II: $52,865 to $1,093,927; Avg $821,791. STTR Phase I: $180,642 to $180,642; Avg $180,642. STTR Phase II: $615,858 to $975,387; Avg $767,351. SBIR/STTR Phase III: none YTD.

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The goal of this funding opportunity announcement (FOA) is to fund meritorious vision-related research projects that involve secondary data analyses using existing database resources. The development of statistical methodology necessary for improving methods to analyze vision health data using existing vision data may also be proposed.

Additional information from the agency ↗

Full announcement & documents

The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.

PAR-25-357 Full Announcement TextFull Announcement · PAR-25-357-Full-Announcement.htmlHTML · 1 KB

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Open the application packageUse opportunity number PAR-25-357 on Grants.gov (Grants.gov Workspace). Open ↗
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyNational Institutes of Health · grantsinfo@nih.gov Open ↗
Submit before October 16, 2027Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listing

What is an ALN?

93.867Vision ResearchProgram →

Reported obligations under ALN 93.867

Historical data · not a prediction

FY24

$696M

FY25

$703M

FY26

$864K est.

Source: SAM.gov Assistance Listing 93.867. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.867

Historical data · not a prediction

Since October 1, 2023, 3,582 grant awards had funding actions under Vision Research, with 1,346 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.

THE JOHNS HOPKINS UNIVERSITY$81.2M
THE LELAND STANFORD JUNIOR UNIVERSITY$63.4M
REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE$55.1M
JAEB CENTER FOR HEALTH RESEARCH FOUNDATION, INC.$52.2M
DUKE UNIVERSITY$46.7M

Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

National Institutes of Health
grantsinfo@nih.gov
301-402-2541

Quick answers

When is the deadline for this opportunity?

According to the official notice, applications are due October 16, 2027. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for this opportunity?

The official notice names these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How do I apply for this opportunity?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-25-357), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedResearchALN 93.867