OpenOpportunity PAR-27-064

NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)

National Institutes of Health · Department of Health and Human Services

At a glance

NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required) is an open federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due July 5, 2029. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.855 (Allergy and Infectious Diseases Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Posted: Jun 16, 2026
Close date: Jul 5, 2029
Archive date: Sep 5, 2029
Est. award date: Dec 1, 2026
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: Not specified
Expected awards: Not specified
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, include mechanistic studies. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities. Support is available for clinical trials up to 5 years, as well as for extended clinical trials of 6- or 7-years.Investigators are encouraged to visit this NIH website for additional information about the overall mission and research areas of NIAID.Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation Cooperative Agreement (U01) application. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.

Assistance Listing

What is an ALN?

93.855Allergy and Infectious Diseases ResearchProgram →

Reported obligations under ALN 93.855

Historical data · not a prediction

FY24

$4.07B

FY25

$4.38B

FY26

$4.3B est.

Source: SAM.gov Assistance Listing 93.855. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

National Institutes of Health
NIAID_IICT_U01@mail.nih.gov
301-402-2541

Quick answers

When is the deadline for “NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)”?

According to the official notice, applications are due July 5, 2029. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for “NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)”?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How do I apply for “NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PAR-27-064), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedALN 93.855