NIH Research Program Projects (Parent P01 Clinical Trial Optional)
National Institutes of Health · Department of Health and Human Services
At a glance
NIH Research Program Projects (Parent P01 Clinical Trial Optional) is a forecasted federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of September 25, 2026; forecast dates can change. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.113 (Environmental Health) and 17 other listings.
Summary assembled from the official notice's fields. The official notice governs.
Key facts
- Posted
- Feb 11, 2026
- Est. close date
- Sep 25, 2026
- Est. award date
- Jul 1, 2027
- Award floor
- Not specified
- Award ceiling
- Not specified
- Est. total funding
- Not specified
- Expected awards
- Not specified
- Cost sharing
- Not required
- Funding instrument
- Grant
- Opportunity category
- Discretionary
- Fiscal year
- FY2027
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public colleges & universities
- Federally recognized tribal governments
- Public & Indian housing authorities
- Native American tribal organizations
- 501(c)(3) nonprofits
- Nonprofits without 501(c)(3) status
- Private colleges & universities
- For-profit organizations (not small businesses)
- Small businesses
- Others (see notice)
Additional information on eligibility (from the notice)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Based on the published notice. Review the official notice for complete eligibility requirements.
What it funds
Official synopsis as published by the agency, formatted for readability.
Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and offices (ICOs) invite applications for investigator-initiated Program Project (P01). A P01 supports a broadly based, multidisciplinary research program with a specific major scientific objective or theme. The proposed Program Project must be related to the programmatic interests of one or more of the participating ICs based on their scientific missions. Each application submitted in response to this NOFO must consist of at least two research projects and an Administrative Core. A P01 may include scientific cores, if needed for the proposed research. Applicants are strongly encouraged to reach out to awarding ICOs to discuss ICO-specific scientific core requirements at least 60 days prior to the receipt date: https://grants.nih.gov/funding/find-a-fit-for-your-research/nih-institutes-centers-offices. The projects included within the Program must share a common central scientific theme, focus, and/or an overall objective.
Assistance Listings
What is an ALN?- 93.113Environmental HealthProgram →
- 93.233National Center on Sleep Disorders ResearchProgram →
- 93.273Alcohol Research ProgramsProgram →
- 93.279Drug Use and Addiction Research ProgramsProgram →
- 93.307Minority Health and Health Disparities ResearchProgram →
- 93.313NIH Office of Research on Women's HealthProgram →
- 93.393Cancer Cause and Prevention ResearchProgram →
- 93.394Cancer Detection and Diagnosis ResearchProgram →
- 93.395Cancer Treatment ResearchProgram →
- 93.396Cancer Biology ResearchProgram →
- 93.399Cancer ControlProgram →
- 93.837Cardiovascular Diseases ResearchProgram →
- 93.838Lung Diseases ResearchProgram →
- 93.839Blood Diseases and Resources ResearchProgram →
- 93.840Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep DisordersProgram →
- 93.855Allergy and Infectious Diseases ResearchProgram →
- 93.866Aging ResearchProgram →
- 93.879Medical Library AssistanceProgram →
Reported obligations under ALN 93.113
Historical data · not a predictionAgency contact (as published)
Referral Officer
Telephone: 240-276-6390
Quick answers
Is “NIH Research Program Projects (Parent P01 Clinical Trial Optional)” open for applications yet?
Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around April 25, 2026. Forecast details and dates can change.
Who is eligible to apply for “NIH Research Program Projects (Parent P01 Clinical Trial Optional)”?
The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.
How do I apply for “NIH Research Program Projects (Parent P01 Clinical Trial Optional)”?
Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PA-27-061), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.
Related open opportunities
Matched on shared Assistance Listings, agency, categories and eligible applicant types.
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Nov 30, 2028
- Who can apply
- State governments, County governments, City or township governments and 12 more
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Jul 12, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Jul 17, 2027
- Who can apply
- State governments, County governments, City or township governments and 12 more
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Jan 7, 2028
- Who can apply
- State governments, County governments, City or township governments and 12 more
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Jan 7, 2028
- Who can apply
- State governments, County governments, City or township governments and 12 more
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
National Institutes of Health- Award range
- Amount not specified
- Closes
- Jan 7, 2028
- Who can apply
- State governments, County governments, City or township governments and 12 more