ForecastedOpportunity RFA-AI-27-017

Cooperative Program for Modeling Clinical Transplantation

National Institutes of Health · Department of Health and Human Services

At a glance

Cooperative Program for Modeling Clinical Transplantation is a forecasted federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of October 9, 2026; forecast dates can change. Total estimated funding is $1.28M across about 3 awards. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.855 (Allergy and Infectious Diseases Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Posted: Apr 9, 2026
Est. close date: Oct 9, 2026
Est. award date: Jul 1, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $1,280,000
Expected awards: 3
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2027

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The National Institute of Allergy and Infectious Diseases (NIAID) will support its mission through the Cooperative Program for Modeling Clinical Transplantation. Advancements of new therapeutics and success in human solid organ transplantation will require innovative and clinically translatable in-vitro and in-vivo systems to model local and systemic immune responses. This program seeks applications including new approach methods (NAMs) and/or refined mouse models that together will promote translation of new therapies to clinical practice. Potential NAMs include immune-competent microphysiological systems, organoids, ex-vivo perfused human organs, precision-cut tissue slices, and computational systems biology models. Applicants must propose models designed to overcome known obstacles to clinical translation in existing NAMS and/or mouse models, reduce reliance on nonhuman primates, and demonstrate relevance to clinical outcomes. Emphasis on data sharing will facilitate reproducibility and establishment of standards and best practices to achieve the program goals. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Assistance Listing

What is an ALN?

93.855Allergy and Infectious Diseases ResearchProgram →

Reported obligations under ALN 93.855

Historical data · not a prediction

FY24

$4.07B

FY25

$4.38B

FY26

$4.3B est.

Source: SAM.gov Assistance Listing 93.855. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

National Institute of Allergy and Infectious Diseases (NIAID)
CPMCT_U01@mail.nih.gov
Please contact via e-mail.

Quick answers

Is “Cooperative Program for Modeling Clinical Transplantation” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around July 10, 2026. Forecast details and dates can change.

Who is eligible to apply for “Cooperative Program for Modeling Clinical Transplantation”?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through “Cooperative Program for Modeling Clinical Transplantation”?

Per the notice, total estimated program funding is $1,280,000 and the agency expects to make about 3 awards.

How do I apply for “Cooperative Program for Modeling Clinical Transplantation”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-AI-27-017), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedALN 93.855