ForecastedOpportunity RFA-AI-28-011

Immune Drivers of Autoimmune Disease

National Institutes of Health · Department of Health and Human Services

At a glance

Immune Drivers of Autoimmune Disease is a forecasted federal cooperative agreement opportunity from the National Institutes of Health (Department of Health and Human Services). The agency's forecast estimates an application due date of June 11, 2027; forecast dates can change. Total estimated funding is $3.6M. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.855 (Allergy and Infectious Diseases Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Posted: Sep 24, 2026
Est. close date: Jun 11, 2027
Est. award date: Mar 1, 2028
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: $3,600,000
Expected awards: Not specified
Cost sharing: Not required
Funding instrument: Cooperative Agreement
Opportunity category: Discretionary
Fiscal year: FY2028

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Immune Drivers of Autoimmune Disease (IDAD) network. This network aims to understand the earliest steps and triggers leading to autoimmunity and flare in humans, with the vision of ultimately preventing autoimmune disease. Priorities include discovering pre-clinical immune mechanisms, developing autoimmunity risk and staging prediction tools and biomarkers, building preclinical cohorts, leveraging remote recruitment and sampling, and artificial intelligence (AI)/big data. This complex, sustained collaboration relies on shared infrastructure to identify common triggers, pathways, and prevention opportunities. An Infrastructure Opportunity Fund (IOF) will be included in the initiative to provide the network the opportunity to conduct collaborative research projects. An IDAD Network Coordinating Center (NCC) will be responsible for administering the IOF and supporting additional coordinating activities amongst IDAD awardees, including the organization of Steering Committee meetings, resource sharing, data harmonization, sample sharing, and administering the IOF. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 2.

Assistance Listing

What is an ALN?

93.855Allergy and Infectious Diseases ResearchProgram →

Reported obligations under ALN 93.855

Historical data · not a prediction

FY24

$4.07B

FY25

$4.38B

FY26

$4.3B est.

Source: SAM.gov Assistance Listing 93.855. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

Division of Allergy, Immunology, and Transplantation
IDAD_U01@mail.nih.gov
Please contact via email.

Quick answers

Is “Immune Drivers of Autoimmune Disease” open for applications yet?

Not yet. It is a forecast — an agency's advance notice of an expected opportunity. The agency estimates posting the full notice around February 26, 2027. Forecast details and dates can change.

Who is eligible to apply for “Immune Drivers of Autoimmune Disease”?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through “Immune Drivers of Autoimmune Disease”?

Per the notice, total estimated program funding is $3,600,000.

How do I apply for “Immune Drivers of Autoimmune Disease”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-AI-28-011), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.

ForecastedALN 93.855