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OpenOpportunity RFA-DK-27-119

Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)

National Institutes of Health · Department of Health and Human Services

At a glance

Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due February 10, 2027. Individual awards are listed as up to $750K, with about 4 awards expected and $4.8M in total estimated funding. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Posted
Jun 16, 2026
Close date
Feb 10, 2027
Archive date
Apr 10, 2027
Est. award date
Jun 1, 2027
Award floor
Not specified
Award ceiling
$750,000
Est. total funding
$4,800,000
Expected awards
4
Cost sharing
Not required
Funding instrument
Grant
Opportunity category
Discretionary

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public colleges & universities
  • Federally recognized tribal governments
  • Public & Indian housing authorities
  • Native American tribal organizations
  • 501(c)(3) nonprofits
  • Nonprofits without 501(c)(3) status
  • Private colleges & universities
  • For-profit organizations (not small businesses)
  • Small businesses
  • Others (see notice)

Additional information on eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Only institutions at which there is a strong ongoing base of digestive and/or liver diseases-relevant research that relates to the proposed theme of the Center are eligible. The already funded research base must have at least $3 million per year in direct costs of supported research within a proposed theme area that is of primary interest to the NIDDK. These may be a mix of Federal and privately funded research awards or research career development awards. However, at least 30 percent of the total funding contributing to the research base must be secured from the NIDDK. Moreover, enough awards within the research base must be Federal to fulfill the requirement that each Biomedical Research Core must be utilized by a minimum of two federally funded Center members. Training grants, education grants, and fellowship awards are not considered part of the research base funding. Since "Facilities and Administration" costs vary considerably between institutions, these must not be included in the calculation of the research base.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding.

Assistance Listing

What is an ALN?

Reported obligations under ALN 93.847

Historical data · not a prediction
FY24$1.97B
FY25$2.04B
FY26$111M est.
Source: SAM.gov Assistance Listing 93.847. Program-wide totals, not awards from this specific opportunity.

Agency contact (as published)

National Institutes of Health
NIDDK_DDN@nih.gov
301-402-2541

Quick answers

When is the deadline for “Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)”?

According to the official notice, applications are due February 10, 2027. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for “Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)”?

The official notice lists these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How much funding is available through “Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)”?

Per the notice, individual awards are listed as up to $750k, total estimated program funding is $4,800,000 and the agency expects to make about 4 awards.

How do I apply for “Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)”?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity RFA-DK-27-119), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.