OpenResearch announcementOpportunity PA-27-035

NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)

National Institutes of Health · Department of Health and Human Services

At a glance

NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed) is an open federal grant opportunity from the National Institutes of Health (Department of Health and Human Services). Applications are due May 5, 2029. Applicant types listed as eligible include state governments, county governments, city or township governments, special district governments, independent school districts and 10 more. Cost sharing is not required. It is funded under Assistance Listing 93.121 (Oral Diseases and Disorders Research) and 22 other listings.

Summary assembled from the official notice's fields. The official notice governs.

Key facts

Jun 8, 2026Posted
May 5, 2029Application deadlinenext date
Apr 1, 2027 (est.)Est. award date
Jul 4, 2029Archived

Posted: Jun 8, 2026
Close date: May 5, 2029
Archive date: Jul 4, 2029
Est. award date: Apr 1, 2027
Award floor: Not specified
Award ceiling: Not specified
Est. total funding: Not specified
Expected awards: Not specified
Cost sharing: Not required
Funding instrument: Grant, Cooperative Agreement
Opportunity category: Discretionary

Typical awards for this program (SAM.gov listing for ALN 93.121, not this notice): FY2023: research project grants: range $10,355-$3,198,621, average $493,453; NRSA: range $12,200-$645,669, average $102,286; SBIR/STTR: range $44,553-$1,265,448, average $734,953; Career development: range $19,566-$283,536, average $151,550. FY2024: research project grants: range $14,491-$3,134,285, average $499,286; NRSA: range $2,500-$689,065, average $117,487; SBIR/STTR: range $44,553-$1,493,635, average $721,489; Career development: range $12,905-$282,170, average $156,332.

Who can apply

State governments
County governments
City or township governments
Special district governments
Independent school districts
Public colleges & universities
Federally recognized tribal governments
Public & Indian housing authorities
Native American tribal organizations
501(c)(3) nonprofits
Nonprofits without 501(c)(3) status
Private colleges & universities
For-profit organizations (not small businesses)
Small businesses
Others (see notice)

Additional information on eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.Institutions with existing Ruth L. Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other Federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving federal support. In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant institution.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to applyNon-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Can your organization apply?

A quick check against the listed applicant types — other requirements in the notice still apply.

Based on the published notice. Review the official notice for complete eligibility requirements.

What it funds

Official synopsis as published by the agency, formatted for readability.

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; andFoster a better understanding of biomedical, behavioral and clinical research and its implications.

Full announcement & documents

The full announcement has the complete rules — page limits, required attachments, evaluation criteria and any letter-of-intent dates. Files download directly from Grants.gov.

PA-27-035-Full-Announcement.htmlFull Announcement · PA-27-035-Full-Announcement.htmlHTML · 164 KB

How to apply

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Read the full announcement (NOFO)Eligibility, evaluation criteria, page limits and required attachments are in the full notice on Grants.gov. Open ↗
Confirm eligibility and fitCheck your organization type above; no cost sharing is required.
Register (or renew) in SAM.gov and get a UEIFree. New registrations can take several weeks; registrations must be renewed every year. Open ↗
Set up Grants.gov accessCreate a Grants.gov account and make sure someone has the Authorized Organization Representative (AOR) role. Open ↗
Open the application packageUse opportunity number PA-27-035 on Grants.gov (Grants.gov Workspace). Open ↗
Prepare narrative, budget and attachmentsFollow the notice's format exactly — page limits and required forms are common reasons applications are rejected.
Ask the agency contact any questions earlyNational Institutes of Health · NIHTrain@mail.nih.gov Open ↗
Submit before May 5, 2029Submit a few days early and keep your Grants.gov confirmation and validation emails.

Assistance Listings

What is an ALN?

Reported obligations under ALN 93.121

Historical data · not a prediction

FY24

$320M

FY25

$332M

FY26

$337M est.

Source: SAM.gov Assistance Listing 93.121. Program-wide totals, not awards from this specific opportunity.

Who was funded under ALN 93.121

Historical data · not a prediction

Since October 1, 2023, 2,560 grant awards had funding actions under Oral Diseases and Disorders Research, with 1,599 sub-awards passed on to other organizations. These are program-wide awards, not awards from this specific notice.

REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE$48.7M
REGENTS OF THE UNIVERSITY OF MICHIGAN$48.5M
UNIVERSITY OF SOUTHERN CALIFORNIA$41.7M
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION$41.5M
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE$35.4M

Recipients, states, recent awards and sub-awards →Source: USAspending.gov.

Agency contact (as published)

National Institutes of Health
NIHTrain@mail.nih.gov
301-402-2541

Quick answers

When is the deadline for this opportunity?

According to the official notice, applications are due May 5, 2029. Confirm the deadline and submission time on Grants.gov before applying.

Who is eligible to apply for this opportunity?

The official notice names these applicant types as eligible: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public colleges & universities, Federally recognized tribal governments, Public & Indian housing authorities, Native American tribal organizations, 501(c)(3) nonprofits, Nonprofits without 501(c)(3) status, Private colleges & universities and 3 more. Additional restrictions may apply; review the full notice.

How do I apply for this opportunity?

Applications are submitted through the official source, not through GrantsJunction. Open the official notice on Grants.gov (opportunity PA-27-035), and review the full announcement and application package. Organizations applying through Grants.gov generally need an active SAM.gov registration and a Grants.gov account, which can take several weeks to set up.

Matched on shared Assistance Listings, agency, categories and eligible applicant types.